Causes and Prevention: Overview

Despite all the attention given to cancer genes in the press, less than 10% of all cancers are inherited.

Cancer cases that are not inherited, 90%

Cancer cases that are inherited, 10%

Many other people would like to blame cancer on synthetic chemicals – but pollution, food additives, and industrial wastes account for less than 5% of cancers in the U.S.  So what is really behind cancer?

Cancer cases caused by synthetic chemicals, 5%.

Cancer cases that are inherited, 10%

A world map can give surprising clues about cancer causes, as well as prevention. Although cancer affects people of all nationalities, epidemiologists look for cancer “hot spots” – regions with high cancer rates. Then they attempt to find environmental, dietary, cultural, or lifestyle factors that are common to the regions where cancers are most frequent.

Cancer Epidemiology


Examine the worldwide distribution of cancer types.

Where is lung cancer most prevalent?

What do the hot spots have in common? Click here to find out.
Environment?
Diet?
Culture?

Lung Cancer: The incidence of lung cancer is directly related to smoking. The highest rates are found in developed countries, where people can afford the luxury of a cigarette habit. Lung cancer cases rose in men following WWII, but have fallen in recent years. Unfortunately, smoking - and lung cancer - are on the rise in women. Lung cancer is the leading cause of cancer deaths in the United States, but deaths would drop 85% if no one smoked.

Where is liver cancer most prevalent?

What do the hot spots have in common? Click here to find out.
Environment?
Diet?
Culture?

Liver Cancer: The incidence of liver cancer is correlated with infection by the Hepatitus B virus, and also to aflatoxin - a powerful mutagen released by mold on peanuts and other foodstuffs. High rates of liver cancer roughly coincide with areas of hepatitis infection and where foodstuffs are improperly stored under damp conditions.

Where is stomach cancer most prevalent?

What do the hot spots have in common? Click here to find out.
Environment?
Diet?
Culture?

Stomach Cancer: Stomach cancer appears to be strongly influenced by diet. The high rates found in Asia are puzzling, but thought to be related to pickled and smoked foods prevalent in the diet.

Where is skin cancer most prevalent?

What do the hot spots have in common? Click here to find out.
Environment?
Diet?
Culture?

Skin Cancer: Most skin cancers are caused by sunlight exposure. Pigments in dark or tanned skin absorb some of the ultraviolet light that is responsible for the DNA mutations behind skin cancers. High rates of deadly melanomas are found mainly in the middle latitudes, where large populations of fair-skinned Caucasian people live. The highest rates are found in dry, sunny climates, where people can spend a lot of time outdoors.

Where is breast cancer most prevalent?

What do the hot spots have in common? Click here to find out.
Environment?
Diet?
Culture?

Breast Cancer: Many people suspect environmental causes are at the root of breast cancer "hot spots." However, a woman's lifetime exposure to estrogen is probably the best predictor of cancer risk. This is roughly measured as the length of time between the onset of menstruation and childbirth. Breast cancer rates are highest in affluent areas, where good nutrition decreases the average age at which girls reach puberty and where working women are most likely to postpone childbirth. A high fat diet also seems to contribute to breast cancer.

Where is cervix cancer most prevalent?

What do the hot spots have in common? Click here to find out.
Environment?
Diet?
Culture?

Cervix Cancer: The incidence of cervix cancer is related to genital wart infection. It is one of the most preventable cancers, since precancerous cells can be detected by a PAP smear. Thus, areas of high incidence correlate with high levels of sexually transmitted diseases and poor routine health care for women.

Where is colon/rectum cancer most prevalent?

What do the hot spots have in common? Click here to find out.
Environment?
Diet?
Culture?

Colon/Rectum Cancers: Colon/Rectum cancersare associated with the high-fat, low-fiber diets found in affluent nations. However, colonoscopy can detect most polyps before they progress to tumors. So colon cancer rates are dropping – about 2% per year in the U.S. – as colonoscopy becomes a routine part of health care in developed countries.